Acronym: SGENE
A large scale genome-wide association study of schizophrenia addressing variation in expressivity and contribution from environmental factors.
Schizophrenia (SZ) is a complex and disabling disorder that continues to exact a heavy toll not only upon those afflicted but also on relatives and on our health and welfare systems. Family history significantly increases the risk of developing the disease and evidence from epidemiological and twin studies continues to support the notion that the genetic risk is the most substantial contributor to its aetiology.
